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These findings elucidate the role of the ACSL4ferroptosispyroptosis axis in pressure-overload-induced heart failure and offer potential therapeutic targets for its prevention

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Persistent senescent cells have been associated with aging or age-related diseases via secretion of proinflammatory cytokines that alter the tissue microenvironment or modify the function of normal cells (Baker et al., 2011)

Therefore, it is recommended that individuals at an elevated risk of bleeding, those taking specific anticoagulants and antiplatelet agents, and those undergoing surgical or other invasive operations should avoid it (Rosenblatt and Mindel, 1997)

De Geer, 2018)

Consequently, clarithromycin-resistant strains of H