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[36]Patra DK, Pradhan C, et al

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While IN DFO has been extensively studied in preclinical models of Alzheimers disease and stroke, recent developments have expanded the scope to other chelators such as DFP

These compounds can neutralize free radicals and reduce oxidative stress, mechanisms implicated in the pathogenesis of several neurodegenerative diseases, including Alzheimers disease and Parkinsons disease (404, 405)

Oxidative stress-related biomarker dysregulations in ASD Our meta-analysis revealed blood oxidative glutathione (GSSG), homocysteine, S -adenosylhomocysteine (SAH), copper, nitric oxide, and malondialdehyde (MDA) concentrations were significantly higher in ASD children than that of HC children, as showed in Table 1 and Figs

Ferroptosis inhibitors can prohibit ferroptosis in activated GPX4-deficient Tregs and maintain their immunosuppressive function in tumors