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Without quitting smoking, even the best treatment options provide only temporary results

However, some studies, including a 2007 report from the Royal College of Physicians in London titled "Harm Reduction in Nicotine Addiction," suggest that some smokeless tobacco products are about 90 percent less harmful than cigarettes

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Ethics statements Patient consent for publication Acknowledgments The authors would like to thank Naruemon Auemaneekul from Mahidol University in Thailand, and Marwah Hassounah from King Saud University in Saudi Arabia, for providing information about plain packaging in their respective countries, and Shira Kislev from Smoke Free Israel for her insight into non-compliance of e-cigarette liquids in Israel