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Measurement of oxidative stress in PsA coincubated with neutrophils To assess oxidative stress in bacteria phagocytized by neutrophils, we measured reduced to oxidized glutathione ratio in PsA coincubated with neutrophils following a previously described method 55

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While it remains difficult to definitively identify CNS macrophages versus microglia in postmortem MS tissue, previous work has found evidence of increased macrophage infiltration in active MS lesions, where they are hypothesized to contribute to chronic inflammation 60