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Description

ATF-2, Activating Transcription Factor 2

Paoli, A., Bianco, A., Moro, T., Mota, J

10.1183/16000617.0021-2019 126 SongX.TanL.WangM.RenC.GuoC.YangB.et al (2021)

doi: 10.1016/j.ajpath.2012.09.016 194 LeeFTCaoZLongDMPanagiotopoulosSJerumsGCooperMEet al

These ROS damage nucleic acids, lipids, and proteins, triggering various adverse cellular effects, including termination of cell division

Mice engineered to express only C/EBP- LAP ( Cebp uORF ) show a marked reduction of age-related impairment and increased lifespan in female animals ( Cebp uORF animals