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Interestingly, iron deficiency also aggravated RM-induced AKI by enhancing catalytic heme-iron-modulated lipid peroxidation and DNA oxidation, upregulating the activity of p53/p21 and promoting cellular senescence [162]

In this review, we discuss the role of cell death mechanisms and explore current frontiers in research, both in humans and animal models, including potential treatment opportunities

The basic mechanisms of the synthesis and insertion of Sec in proteins, their characterization, the molecular and physiological functions of selenoproteins, and their roles in human health were reviewed by Vyacheslav [46]

Factors such as genetic predisposition, poor diet, smoking, and certain medical conditions can contribute to high homocysteine levels

Numerous factors, such as exposure to the sun, hormonal fluctuations, inflammation, or even skin injuries, can cause this

Furthermore, achieving efficient delivery of Exos to affected tissues remains a major challenge