c-terminus of lipid ii II: A central component in bacterial cell wall synthesis and a target for antibiotics Minimal exposure of lipid II
Minimal exposure of lipid II cycle intermediates triggers cell wall antibiotic resistance Nature Communications Synthesis of lipid linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa Nature Microbiology Lipid II: Total Synthesis of the Bacterial Cell Wall Precursor and Utilization as a Substrate for Glycosyltransfer and Transpeptidation by Penicillin Binding Protein (PBP) 1b of Eschericia coli Journal of the Lipid II overproduction allows direct assay of transpeptidase inhibition by lactams Nature Chemical Biology Towards the Native Binding Modes of Antibiotics that Target Lipid II MedeirosSilva 2019 ChemBioChem Wiley Online Library Lipid II as a target for antibiotics Nature Reviews Drug Discovery
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