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WangJWuNPengMOyangLJiangXPengQet al

Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

Abstract Ferroptosis differs from traditional cell death mechanisms like apoptosis, necrosis, and autophagy, primarily due to its reliance on iron metabolism and the loss of glutathione peroxidase activity, leading to lipid peroxidation and cell death

Ethics declarations Competing interests X.J., J.C

In polyphenols, the phenolic OH has a lower dissociation enthalpy than the OH of an aliphatic alcohol (such as ethanol or propanol), so that dissociation can occur in a slightly basic medium in the presence of a radical R or a bivalent metal cation (Figure 18)