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Side Effects & Safety Nausea 44% in STEP trials, most common side effect, dose-dependent Diarrhea 30% in trials Vomiting 24% in trials Constipation 24% in trials Stomach pain 20% in trials Pancreatitis rare but documented

Furthermore, the center region of the NP exhibits additional heterogeneity as indicated by the presence of a distinctive set of transcripts that are involved in cell pluripotency ( Sox2 and Oct4 ) and the development of the notochord ( Noto and T ) and axial skeleton ( Shh and Gli3 )

IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo

Luminal solutes and ions can pass across the IEB via two main routes: the transcellular pathway or the paracellular pathway

Vitamin B12 also supports the nervous system