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They are: Heaviness in legs , unbearable pain with cramps and soreness Discomfort and itching throughout your leg Frequent aches and a warm feeling in the leg Discoloration, thickening, or ulceration of skin in the leg Swelling in the leg Deep vein thrombosis carries the risk of pulmonary embolism

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The burden of gallstone disease in Europe

The main clinical features of Sengers syndrome are hypertrophic cardiomyopathy, bi-sided cataracts, myopathy, and lactic acidosis

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