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Myeloproliferative disorders

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Molecular Characteristics Complete Specifications: Molecular Weight: 1,815.08 Da Molecular Formula: CHNOS Amino Acid Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe Peptide Length: 16 amino acids Peptide Classification: hGH C-terminal fragment (176-191), modified with Tyr177 Disulfide Bond: Cys7-Cys14 (corresponding to Cys182-Cys189 in hGH) Appearance: White to off-white lyophilized powder Solubility: Water, bacteriostatic water, phosphate buffered saline The peptides 16-amino acid structure corresponds to the C-terminal region of human growth hormone with a single modification: tyrosine replaces phenylalanine at position 177 (position 1 in the fragment)

The enrichment was sub-cultured (eight times to remove carryover from the environmental sample) in a simulated Europan fluid medium before inoculating the simulation experiment, as shown in Figure 1