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5.3.3 Ginsenoside Re Ginsenoside Re, an important active component in ginseng, is a tetracyclic triterpenoid derivative known for its significant hypoglycemic effects (127)

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PKM2 succinylation at K498 enhances PKM2 activity and inhibits cell proliferation, whereas SIRT5 promotes tumor growth by preventing succinylation inhibitory activity at this site [85]