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Supportive therapies are now only enabling to prevent a deterioration of cases once at the hospital or ahead of time to avoid intubation

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Tamarind seed polysaccharide hydrolysate ameliorates dextran sulfate sodium-induced ulcerative colitis via regulating the gut microbiota

Conclusion: Our findings suggest that BAP1 mutational inactivation confers cholangiocyte resistance to ferroptosis thus promoting malignant transformation, and that ferroptosis exerts therapeutic benefits in vivo in CCA

In addition to DNAm, cigarette smoking is linked to the activation of enzymes that regulate other types of epigenetic modifications (i.e., post-translational modifications of histones via methylation, acetylation, phosphorylation, ubiquitination, and regulation of non-coding RNA sequences) to mediate the expression of multiple inflammatory genes, thereby participating in the onset development of autoinflammatory diseases (135)