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It is essential to distinguish medically indicated B12 replacement therapy from commercially marketed wellness injections, as they serve fundamentally different purposes and are subject to different regulatory oversight

Daratumumab eliminates the subset of CD38 + Tregs, while Tregs without CD38 expression are not affected [5]

Engelke UF, van Outersterp RE, Merx J, van Geenen FA, van Rooij A, Berden G, et al

J., Mikhail, M

S., Lee, M

2 Currently, there is no curative treatment established for ALS, and since there are only limited number of medicines approved in Japan and abroad, this is a disease with significant unmet medical needs