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prausnitzii bacterial counts are significantly lower in IBD patients versus healthy controls (standardized mean difference -0.94, 95% CI -1.07 to -0.80), further validating butyrate-producing bacterial depletion as a consistent feature of IBD pathology

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Nerve tissue heals at a biologically fixed rate of 1 to 3mm per day under ideal conditions, making blood supply and inflammation control the two critical factors in recovery

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