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SIPS can be caused by various factors including persistent exposure to cell stress, namely, oxidative stress or DNA-damaging mediators 28,29

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The study found that while low to moderate doses (2.5-250 g) provided some benefit, daily doses of around 500 g or more were required to restore healthy B12 levels

doi: 10.1186/s13104-019-4453-3 115 ZhangMBenerMBJiangZWangTEsencanEScottRet al

Gutteridge, J