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The diagnosis was confirmed by the presence of chromosomal translocation t(12;22)(q13;q12)

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in fact, HDL may even be decreased in response to PPAR these species [117]

A second way in which glutaminederived glutamate contributes to glutathione biosynthesis is through facilitating the uptake of cystine via the xCT transporter, which is coupled to the efflux of glutamate (Fig 2)