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In conclusion, the results in this article suggested the need for pre-surveillance to evaluate the immunogenicity of GX-G3 and demonstrate the feasibility of these analytical procedures, which was importantly concerned with the implication of accurately interpretation of toxicokinetic data of recombinant G-CSF drugs in preclinical as well as clinical studies

PMID 29733881

Guruprasad, P, Carturan, A, Zhang, Y, Cho, JH, Kumashie, KG, Patel, RP, Kim, KH, Lee, JS, Lee, Y, Kim, JH, Chung, J, Joshi, A, Cohen, IJ, Shestov, M, Ghilardi, G, Harris, J, Pajarillo, R, Angelos, M, Lee, YG, Liu, S, Rodriguez, J, Wang, L , Ballard, HJ, Gupta, A, Ugwuanyi, O, Hong, SA, Bochi-Layec, AC, Sauter, CT, Chen, L, Paruzzo, L, Kammerman, S, Shestova, O, Liu, D, Vella, LA, Schuster, SJ, Svoboda, J, Porazzi, P, Ruella, M

PMID: 35658525

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It has an anti-inflammatory effect and reduces oxidative stress, and has been shown to be beneficial in human heart disease