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doi: 10.4061/2011/327089 212 ZielenSTrischlerJSchubertR

The prevailing theory prior to this structure was that an open lipase conformation was defined by a displaced lid peptide, exposing the hydrophobic pocket surrounding the active site

Una mujer de 45 aos, sin antecedentes personales de inters y sin tratamiento habitual, acudi a urgencias por la aparicin unos das antes en el abdomen, las caderas y los muslos de mltiples placas eritematoedematosas pruriginosas y dolorosas, de contornos geogrficos purpricos, en algunas zonas confluentes alcanzando gran tamao (fig

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However, Cys 199 oxidation renders the adjacent activation loop Thr 197 phosphorylation site susceptible to phosphatases

Nicholls SJ, Andrews J, Kastelein JJP, Merkely B, Nissen SE, Ray KK, Schwartz GG, Worthley SG, Keyserling C, Dasseux JL, Griffith L, Kim SW, Janssan A, Di Giovanni G, Pisaniello AD, Scherer DJ, Psaltis PJ, Butters J