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Five days later, the patient returned to his oncology clinic with fatigue and dark red urine

Miku, P

Cisplatin treatment has been associated with several toxic side effects including nephrotoxicity (de Jongh, van Veen et al., 2003), hepatotoxicity and Cardiotoxicity (Al-Majed, 2007)

Interleukin-1 beta (IL-1), Interleukin-6 (IL-6), and Tumor Necrosis Factor-alpha (TNF-) are key pro-inflammatory cytokines involved in immune responses and inflammation

These challenges have compelled researchers to accelerate efforts to find new solutions to this growing health crisis

The helical element downstream of the FDF motif is anchored via its highly conserved Phe305 LSM14 by hydrophobic interactions with a second pocket lined with Tyr315 DDX6 , Ile438 DDX6 , and Leu446 DDX6 (Fig 4C)