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Amorphous silica typically has a much higher specific surface area and more silanol (SiOH) groups than crystalline quartz, enhancing As adsorption through ligand exchange or hydrogen bonding (149)

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Taken together, these observations suggest that except in vitamin B 12 deficiency (which only responds to cyanocobalamin treatment because of the inactivation of methionine synthase), folate treatment should be the most adequate therapy to reverse hyperhomocysteinemia detected both under basal conditions and after an oral methionine load