lippard glutathione cisplatin

lippard glutathione cisplatin New drug candidate shows promise against cancer | MIT News A cisplatin-based platinum(IV) prodrug containing

Name: lippard glutathione cisplatin New drug candidate shows promise against cancer | MIT News A cisplatin-based platinum(IV) prodrug containing
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A cisplatin based platinum(IV) prodrug containing a glutathione s transferase inhibitor to reverse cisplatin resistance in non small cell lung cancer ScienceDirect Systems biology of cisplatin resistance: past, present and future Cell Death & Disease Bucillamine prevents cisplatin induced ototoxicity through induction of glutathione and antioxidant genes Experimental & Molecular Medicine Metabolic reprogramming and cisplatin resistance: the emerging role of Pyruvate Dehydrogenase Kinases (PDKs) Cell Communication and Signaling Springer Nature Link Is Glutathione the Major Cellular Target of Cisplatin? A Study of the Interactions of Cisplatin with Cancer Cell Extracts Journal of Medicinal Chemistry Schematic diagram of GSH related elimination of cisplatin and of Download Scientific Diagram

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10.1016/j.scitotenv.2023.162101 219 Jimnez-ArroyoC.TamargoA.MolineroN.ReinosaJ

monocytogenes has perhaps the most complex relationship with GSH that has been described, as it not only imports GSH as a cysteine source with a dedicated GSH transporter 19 , but it senses the host reducing environment and synthesizes its own GSH that post-translationally modifies and activates the master virulence transcription factor PrfA 16,17,18