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When combined, these results emphasize how crucial it is to take the entire dietary context into account when analyzing the clinical outcomes of specific antioxidant treatments in PCOS

Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin

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The first one includes soluble dimeric enzymes localized mainly in cytosole but certain members of this superfamily have been also identified in mitochondria (Robinson et al., 2004) or in peroxisomes (Morel et al., 2004)

These findings establish ferroptosis as a key mechanism in myoglobin-induced nephrotoxicity ( Figure 5 )