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In terms of mechanism, astaxanthin can cross the bloodbrain barrier (Petri and Lundebye, 2007) to exert its antioxidant (Pan et al., 2017), anti-inflammatory (Zhang et al., 2017b), and neuroplastic effects on the brain

Meanwhile, epigenetic regulation of a gene usually requires more than one epigenetic event

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As the terminal electron acceptor for oxidative phosphorylation, molecular oxygen occupies an essential role in many of the metabolic processes associated with aerobic existence [14]