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The vaccine-induced immune thrombocytopenia and thrombosis (VITT) is a rare but severe adverse effect of post-COVID-19 vaccination, characterized by thrombocytopenia and major venous or arterial thrombosis

Low extracellular zinc increases neuronal oxidant production through nadph oxidase and nitric oxide synthase activation

It targets concerns such as acne, rosacea, hyperpigmentation, and signs of aging while stimulating collagen for smoother, healthier skin

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The evidence base requires appropriate clinical trials, with additional endpoints including clinical symptoms of patients and additional biochemical parameters beyond plasma B12 levels alone before these alternative routes can be recommended with confidence in clinical guidelines