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Because the risk of bleeding may be higher, tell your doctor before using fondaparinux sodium injection if you: are also taking certain other medicines that affect blood clotting such as aspirin, an NSAID (for example, ibuprofen or naproxen), clopidogrel, or warfarin sodium have bleeding problems had problems in the past with pain medication given through the spine have had surgery to your spine have a spinal deformity See What are the possible side effects of fondaparinux sodium injection? for more information about side effects