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Limitations The most common physiological marker for oxidative stress is decreased GSH/GSSG ratio [5,63]

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It occupies the P2 site (used for the binding of pyrophosphate and -alanine) of Mtb PS, and its OMe group and sulfone oxygen make hydrogen bonds with the backbone nitrogen of Val187, and both the backbone amide group of Met40 and the side chain of His47, respectively (Fig

Based on these complex pathogenesis processes, drug nebulization for COVID-19 pneumonia with different mechanisms of action have been investigated, including anticoagulants [15,16,17,18,19,20], antioxidants [21,22,23], corticosteroids [24,25,26], and bronchodilators [27, 28]

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