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MC-Val-Cit-PAB(m-PEG8)-Exatecan m-peg4 3-benzodiazole Synonyms CAS Number n/a

MC-Val-Cit-PAB(m-PEG8)-Exatecan m-peg4 3-benzodiazole Synonyms CAS Number n/aSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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Description

3-benzodiazole Synonyms CAS Number n/a Related CAS Molecular Formula C8H7BrN2 Molecular Weight 214

SiR-Azide is a far-red fluorescent probe containg azide moiety for click chemustry apploications

CA-PEG4-amide-PEG4-Bition is a Biotin-HaloTag ligand that enables rapid labeling of Halo-tagged proteins and their efficient isolation via streptavidin pull-down

5-ROX azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through the well known click chemitry

Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in antibody–drug conjugate (ADC) development

MC-Val-Cit-PAB(m-PEG8)-Exatecan m-peg4 3-benzodiazole Synonyms CAS Number n/aSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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