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Third-party tested, COA included

TABLE 5 In vivo Studies Using BALB/c Mice

As put by the authors of a 2019 review on drug-phospholipid complexes, the combined affinity for fats and water means that phospholipids function as emulsifiers that enhance absorption and, therefore, bioavailability.4 Indeed, a 1990 human study found that a silymarin-phospholipid complex resulted in plasma levels of silybin (silymarin's main active component) that were more than double the amount provided by an equal quantity of pure silymarin 298ng/mL versus 102ng/mL per 120mg of silybin.34 Given the science behind phospholipid-based drug delivery, we can conclude that Life Extension is likely capable of delivering more per-dose silymarin, as well as isolated silybin, than either NOW or HUM (neither of which uses phospholipids)

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Mental health conditions A review published in Frontiers in Neuroscience discusses an association between markers of inflammation and pessimism, as well as the interplay between these, stress and depression (3)