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Jones D, Carlson JL, Mody VC, Cai J, Lynn M, Sternberg P

Am J Pediatr Hematol Oncol

Okay, that's the pathway

Specifically modified nanocarriers delivering targeted drugs can clear damaged mitochondria by initiating the mitochondrial autophagy program, effectively restoring mitochondrial homeostasis, reducing the neurotoxicity caused by oxidative stress, and rescuing the motor dysfunction in animal models

Tanabe S, OBrien J, Tollefsen KE et al (2022) Reactive oxygen species in the adverse outcome pathway framework: toward creation of harmonized consensus key events