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This enhanced tolerance could be relevant to the increased transcription of the GSH cycle-related genes and increased GSH content and biosynthesis, and decreased the transcription of Cd transporter genes

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Nrf2 transcriptionally activates GGT [29], which plays a key role in glutathione homeostasis by breaking down extracellular glutathione into its constituent parts, which can be taken up by the cell for intracellular glutathione synthesis [30]

Parkinsons disease affects the central nervous system and is defined by symptoms such as tremors

Studies suggest that maintaining adequate glutathione levels helps preserve the integrity of neural membranes and supports the cellular processes involved in synaptic transmission