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measured MMP1, MMP2, TIMP1, and TIMP2 gene expression in human adult dermal fibroblasts exposed to GHK-Cu at 0.01, 1, and 100 nanomolar concentrations and found dose-dependent increases in both MMPs and their inhibitors 11

This breadth of action may explain why some users respond better to copper peptides when minoxidil hasn't worked

This dual actionrepairing and rebuildingmakes it one of the most advanced ingredients in modern skincare

The active ingredients (PDRN, GHK-Cu, AHK-Cu, biomimetic peptides) target the hair follicle and scalp at a cellular level, not the hair shaft, so hair type does not affect efficacy

When caspase-3 is activated, it cleaves PARP into fragments a hallmark of apoptosis

It is also, in the specific arena of stimulating scalp hair growth, a compound whose human clinical record is thin, indirect, and easily overstated by the wellness market that surrounds it