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This window allows the peptide to reach peak plasma concentration and begin binding NNMT enzymes before dietary nicotinamide from food enters the system

Biomed Pharmacother Biomedecine Pharmacother 93:13101319 Smith GI, Shankaran M, Yoshino M, Schweitzer GG, Chondronikola M, Beals JW et al (2020) Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease