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"Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis." Proc Natl Acad Sci

Targeting glycolysis impacts the accumulation of PD-1+ TILs in PDAC preclinical models [295]

Shikonin derivatives inhibited LPS-induced NOS in RAW 264.7 cells via downregulation of MAPK/NF-kappaB signaling

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J Neurochem 78:13891399 Crack PJ, Taylor JM, Ali U, Mansell A, Hertzog PJ (2006) Potential contribution of NF-B in neuronal cell death in the glutathione peroxidase-1 knockout mouse in response to ischemia-reperfusion injury