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Monitor INR more frequently in patients with compromised renal function to maintain INR within the therapeutic range [see Warnings and Precautions (5.4) and Use in Specific Populations (8.6)]

UK pregnancy guidance advises limiting tuna to two steaks or four medium-sized cans per week, avoiding shark, swordfish and marlin completely, and limiting oily fish to two portions weekly

By following these guidelines, patients can safely and effectively administer their vitamin B12 injections at home

[2] Treatment Initial treatment Infants breastfeeding from an individual with vitamin B 12 deficiency: IM cyanocobalamin followed by either PO cyanocobalamin OR vitamin B 12 -enriched food or formula [1] [2] Children Asymptomatic children with mild deficiency and no concern for malabsorption or nonadherence: high-dose PO cyanocobalamin once daily [1] [4] [13] [17] All others: IM cyanocobalamin [1] Adolescents: Treatment is similar to treatment of vitamin B 12 deficiency in adults