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The lack of B12 affects the production of red blood cells, leading to reduced oxygen transport and poor muscle function

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In mammals, Trp is an essential amino acid and is a precursor for several important metabolites such as serotonin, melatonin, and nicotinamide adenine dinucleotide (NAD + ) 46

J Clin Invest

Studies have indicated that, in human NAFLD patients, increased PARP activity could potentially lead to NAD + depletion and mitochondrial dysfunction 164

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