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Importantly, the enzymatic activity of TETs is regulated by 2-oxoglutarate (2OG) as a cofactor and suppressed by metabolites such as 2-hydroxyglutarate (2HG) as a competitor of 2OG

7, G and H), while the volume of A also significantly increased in CD206 BAMs (Fig

Both Neh 4 and Neh 5 also function as transactivation domains which are involved in the interaction with cAMP response element-binding protein (CREB)-binding protein (CBP) and receptor-associated coactivator 3 (RAC 3)

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