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It results from axonal injury and abnormal death of oligodendrocytes, which are highly susceptible to oxidative damage

They concluded that increased levels of circulating vitamin D were significantly associated with a reduced risk of migraines (106)

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4.5 Synergistic versus antagonistic potential These mechanistic overlaps provide a compelling rationale for a combinatorial therapeutic assault

Biochem J 411:571579 Banci L, Bertini I, Chasapis CT et al (2007) Interaction of the two soluble metal-binding domains of yeast Ccc2 with copper(I)-Atx1