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Description

The activation of the NF-B signaling pathway can also promote the activation of sterol regulatory element binding protein (SREBP), upregulating the expression of downstream enzymes involved in fatty acid synthesis (such as elongases and fatty acid synthase), inducing significant fatty acid synthesis and further promoting the polarization of macrophages towards the M1 phenotype

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[DOI] [PubMed] [Google Scholar] 139.Radwan SM, Alqulaly M, Elsaeed MY, Elshora SZ, Atwa AH, Wasfey EF

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