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Regulation of proapoptotic proteins Bak1 and p53 by miR-125b in an experimental model of Alzheimers disease: protective role of 17beta-estradiol

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In reactive astrocytes, MAO-B activity is notably elevated, leading to increased production of H 2 O 2 , while NADPH oxidase 2 is frequently upregulated, further amplifying ROS generation [359, 363]