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standardized curcumin 95%) was administered orally for 28 days at 50, 100 or 200 mg/kg, and its effects were assessed through an extensive battery of neurobehavioral tests alongside biochemical analyses of whole-brain tissue

196 The NAD + -consuming enzymes, PARPs, are associated with the regulation of DNA modification

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This barrier is made of a single layer of cells held together by "tight junctions." When these junctions are compromiseda concept sometimes referred to as "leaky gut" or intestinal permeabilityirritants can pass through into the bloodstream

Those are all factors

doi: 10.1186/s13099-018-0258-5 14 ChoeJ