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A conjugate according to claim 1, wherein the steroidal agent is selected from the group consisting of hydrocortisone, cortisone acetate, prednisone, prednisolone, methylprednisolone, methylprednisolone acetate, methylprednisolone hemisuccinate, dexamethasone, betamethasone, triamcinolone, beclometasone, fludrocortisone acetate, fludrocortisone hemisuccinate, deoxycorticosterone acetate, deoxycorticosterone hemicussinate, and aldosterone

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More recent studies have revealed the existence of an alternative modification, 5'-hydroxymethylcytosine (5hmC), which is formed by oxidation of 5mC by ten-eleven translocation (TET) enzymes (Kriaucionis and Heintz, 2009

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