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[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Solomon L.R

Despite their efficacy, betablockers can be associated with significant adverse effects

With time, these alterations can induce mitochondrial dysfunction, facilitating cell death mechanisms like ferroptosis

Increased vascularization supports nutrient delivery and waste removal, which are important for oocyte quality and embryo implantation

Besides, saikosaponin A activates IL-12/STAT4 pathway to increase serum IFN- and IL-12 levels and decreases in serum IL-4 and IL-10 levels, which shift Th1/Th2 balance toward Th1 [259]