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Improved Skin Texture: Reduces inflammation and promotes cell turnover, leading to smoother and more radiant skin

In contrast, miR-101 is highly expressed in M2 macrophages (pro-tumor) and suppresses C/EBP and KLF6, promoting M1-to-M2 polarization

Liver tissue was analyzed for fibrosis and inflammation markers by immunohistochemistry, qPCR and western blotting

Overload of mitochondria with ammonium instigates over-production of reactive oxygen species and opening of mitochondrial permeability transition pore, which further damages astrocytes and induce astrocyte swelling

Statistical analysis All data were obtained from in vitro experiments in 48 or 96 well plates, with each individual well considered a pseudo-biological replicate

2.2 Data acquisition MRI: All data were collected on a Philips 3T Ingenia Elition RX scanner (Philips Healthcare, Best, the Netherlands) equipped with a 32-channel receive-only head coil