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Tesfamariam et al

In the patient group, the mean age of onset was 24.90 5.56 years and the duration of illness was 11.15 9.11 years

Presence of gallstones and cholecystitis

46,460,463 A recent study has revealed that blimekizumab and adalimumab have similar effects in the treatment of psoriatic arthritis and plaque psoriasis and that bimekizumab is associated with better skin clearance than secukinumab

The two drugs differ in their mechanisms: Dupilumab is a dual-acting antibody that blocks both IL-4 and IL-13 signaling, while Lebrikizumab, developed by Eli Lilly, is a single-acting antibody that selectively blocks only IL-13

The combination is hypothesized to cover more of the repair cascade simultaneously