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These abnormalities lead to neural dysfunction, synaptic loss, and ultimately, neuronal death

The functional interactome of GSTP: A regulatory biomolecular network at the interface with the Nrf2 adaption response to oxidative stress

Only one of these, the 8,9-exo-epoxide, appears to be mutagenic and the others are detoxification products

190 HeimMIrondelleMDuteilLCardot-LecciaNRocchiSPasseronTet al

The fluorescence intensity was measured to quantify the concentration of GSH at ex = 365 nm

Despite its documented efficacy in vitro and in vivo in alleviating oxidative stress and preventing iron deficiency, Fer-1 remains untested in clinical trials (114)