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A pre-specified BBBP disruption threshold of 21% resulted in a sensitivity of 37.5% and a specificity of 80% for the prediction of parenchymal hematoma, with a positive predictive value of 0.375 (177)

In vivo rodent models have explored the pharmacokinetics and tissue distribution of Proxofim, examining whether the protease-resistant DRI backbone achieves sufficient systemic exposure and tissue penetration

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Next, we identified DEGs between the control group and the WT group, the (-)-Vestitol group and the control group, the Salviolone group and the control group, and the combination group and the control group

It can also promote faster wound healing

The absence of a significant effect with CBBBP alone suggests that the CBBBP construct may require the DSIP component to engage with the relevant neural pathways effectively