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2.5 Histological assessment of IENF density The sensory disturbance observed in CIPN patients is often associated with the loss of sensory nerve fibers, as reflected by a prominent reduction in intraepidermal nerve fibers (IENFs) in skin biopsies and mouse model of CIPN (Siau et al., 2006

10.1038/nchembio.2239 63 DoshiB

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Protein lysates were then centrifuged at 13,300 rpm for 10 min and the supernatant was collected