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After neutralization with 0.5 M phosphate buffer (7.5), 0.1 mL of the supernatant was added to a reaction mixture containing 0.2 mM NADPH, 100 mM phosphate buffer (pH 7.5), 5 mM EDTA, and 0.6 mM 5,5dithio-bis (2-nitrobenzoic acid)

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In men with mild BPH, watchful waiting may be appropriate annual exams and completion of the American Urological Association Symptoms Index (AUASI) In men with moderate-to-severe BPH, pharmacological treatment can be considered: 1-adrenergic receptor blockers such as alfuzosin (Uroxatral) and terazosin 5-reductase inhibitors such as finasteride (eg, Proscar, Propecia) and dutasteride (Avodart) Antimuscarinics such as darifenacin (Enablex) and tolterodine (eg, Detrol) Phosphodiesterase-5 inhibitors such as tadalafil (Cialis) Surgery to remove the prostate or reduce its size What are Emerging Therapies for Benign Prostatic Hyperplasia

Superoxide dismutase (SOD) SOD was discovered in 1967 by Irwin Fridovich (McCord and Fridovich 1969)