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[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Faraj S., Kemp E.H., Gawkrodger D.J

By completing your purchase, you acknowledge that Melanotan I (Afamelanotide) is an investigational material not approved for general medical or therapeutic use by any regulatory authority

Urology, 2000 Effect of alpha-MSH analog on penile erection and sexual desire in organic ED Hadley & Dorr Peptides, 2006 Melanocortin peptide therapeutics: historical milestones and clinical studies En esta pgina Melanotan II es un anlogo sinttico cclico de la hormona estimulante de melanocitos alfa (-MSH)

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Specifications Identity: Melanotan II (MT-II) cyclic -MSH analogue Synonyms: MT-II, Melanotan-2 CAS Number: 1036322-26-5 General Structure: Ac-Nle-cycloAspHisDPheArgTrpLysAsp-His-D-Phe-Arg-Trp-Lys-NH (lactam bridge) Molecular Weight: ~ 1024.2 g/mol Appearance: White to off-white lyophilized powder Purity: 99% (HPLC/MS verified) Form & Sizes: Common research and clinical vials 10 mg Manufacturing: GMP-compliant facility, USA Storage: 20 C, desiccated

Understanding Melanotan-1 Mechanism and Receptor Selectivity Melanotan-1 (afamelanotide, [Nle4-D-Phe7]--MSH) is a synthetic analog of alpha-melanocyte-stimulating hormone (-MSH), engineered with amino acid substitutions at positions 4 and 7 that increase receptor binding affinity and extend serum half-life to approximately 33 minutes following subcutaneous injection